post mortem tissue samples

Standard body bagging procedures should be followed, consistent with procedures used for deaths where COVID-19 is not suspected.

The idea to implement CT guidance for post-mortem tissue sampling was born with the expansion of CT and its … Guidelines For Submitting Specimens to CDC. Limit the number of personnel working in the autopsy suite at any  time to the minimum number of people necessary to safely conduct the autopsy. Focused sampling of these tissues, collected by autopsies limited to the chest, or by directed collection accomplished by incision, can be used when deemed appropriate. Formalin-fixed (wet) tissues or formalin-fixed, paraffin-embedded (FFPE) tissue blocks from lung or upper airway: If  >4 weeks have elapsed since autopsy, original FFPE tissue blocks from the time of autopsy are available. Leave swab in place for several seconds to absorb secretions. HCP should follow Standard Precautions. Note that clinical laboratories should NOT attempt viral isolation from specimens collected from known or suspected COVID-19 cases. Formalin-fixed, and formalin-fixed-paraffin-embedded tissue specimens, obtained at autopsy, can be used to establish a postmortem diagnosis of COVID-19 infection by using immunohistochemical and molecular techniques available at the CDC’s Infectious Diseases Pathology Branch (IDPB). AIIR room air should never be recirculated in the building, but directly exhausted outdoors, away from windows, doors, areas of human traffic or gathering spaces, and from other building air intake systems. Workers receiving the biological specimen bag outside the autopsy suite or anteroom should wear disposable nitrile gloves. Use routine cleaning and disinfection procedures (e.g., using cleaners and water to pre-clean surfaces) prior to applying Environmental Protection Agency (EPA)-approved disinfectantsexternal iconexternal icon that meet the criteria for use against SARS-CoV-2, the virus that causes COVID-19.

Hard, nonporous surfaces may then be cleaned and disinfected as described above. You also have the option to opt-out of these cookies. Serology results are available for each donor, although all human materials must be treated as potentially infectious. Please view our privacy policy for further information.
The EOC will assist local/state health departments to collect, store, and ship specimens appropriately to CDC, including during afterhours or on weekends/holidays. Current evidence suggests that novel coronavirus may remain viable for hours to days on surfaces made from a variety of materials. A logbook including names, dates, and activities of all workers participating in the postmortem and cleaning of the autopsy suite should be kept to assist in future follow up, if necessary. Keep camera, telephones, computer keyboards, and other items that remain in the autopsy suite (or anteroom, if applicable) as clean as possible, but treat as if they are contaminated and handle with gloves. When collection of a postmortem NP swab is not possible, each of the following is an acceptable alternative: Use only synthetic fiber swabs with plastic shafts. Please contact us to find out how our post mortem partner site can meet your research needs with cadaver tissue. When respirators are necessary to protect workers, employers must implement a comprehensive respiratory protection program in accordance with the OSHA Respiratory Protection standard (, An anterior nares (nasal swab; NS) specimen, Nasopharyngeal wash/aspirate or nasal aspirate (NA) specimen. This document provides specific guidance for the collection and submission of postmortem specimens from deceased known or suspected COVID-19 cases. Postmortem swab specimens for COVID-19 testing: Upper respiratory tract swab: Nasopharyngeal Swab (NP swab), Lower respiratory tract swab: Lung swab from each lung, Separate swab specimens for testing of other respiratory pathogens and other postmortem testing, as indicated, Formalin-fixed autopsy tissues from lung and upper airway, Postmortem Nasopharyngeal Swab (NP swab) specimen for COVID-19 testing, Separate NP swab for testing of other respiratory pathogens.

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